Chris Jacobsen
Professor

Chris Jacobsen's work is aimed at the development and applications of high resolution X-ray imaging modalities. He, in collaboration with Professor Kirz and their students, built several scanning transmission X-ray microscopes which make use of two beamlines at the National Synchrotron Light Source at nearby Brookhaven National Laboratory. These microscopes use microfab-ricated diffracted optics (zone plates) to focus the bright beam of X-rays to a 50 nm spot which is used to explore the specimen. Chemical and elemental information is gained using absorption spectroscopy at any desired location. Wet specimens up to 10 microns thick may be examined at room temperature or in a frozen hydrated form at liquid nitrogen temperature to reduce radiation damage. Jacobsen was a Presidential Faculty Fellow (NSF/White House, 1992-1997), and received the International Dennis Gabor Award in 1996.

Ph.D. - State University of New York at Stony Brook, 1988

Phone: (631) 632-8903
Email: Chris.Jacobsen@sunysb.edu
URL: http://xray1.physics.sunysb.edu/~jacobsen/
 

Jolyon Jesty
Professor

Jo Jesty's research is done in collaboration with colleagues in the Department of Applied Mathematics and Statistics and the Department of Biomedical Engineering. His main interest is how the control mechanisms of blood coagulation interact to minimize the response of the system to low stimulus levels; in other words, the prevention of the abnormal responses that cause thrombosis. This involves a two-pronged approach of experimental kinetic studies in parallel with mathematical analysis and numerical simulation of the control systems involved. Jesty's particular focus is the controls that operate in the initiation of coagulation, in which two inhibitors are involved, along with three positive feedbacks. Additionally, a recent collaborative project concerns the effect of prosthetic heart valves on platelet function, and particularly the ways in which they damage platelets. Jesty has published in the areas of both biochemistry and applied mathematics in Biochemistry, Proceedings of the National Academy of Sciences, and many other journals. He is also an associate editor of the journal Haemostasis.

D.Phil. - Oxford University, 1972

Phone: (631) 444-2059
Email: JJesty@mail.som.sunysb.edu
URL: http://ms.cc.sunysb.edu/~jjesty/
 

Arie E. Kaufman
Professor

Arie Kaufman is the director of the Center of Visual Computing (CVC) and the director of the Cube project for volume visualization supported by the National Science Foundation, Department of Energy, Office of Naval Research, Hughes Aircraft Company, Hewlett-Packard Company, Silicon Graphics Company, Howard Hughes Medical Institute, and many others. His research interests include computer graphics and specifically computer graphics architectures, algorithms, and languages; visualization including volume visualization and scientific visualization; user interfaces; virtual reality; and multimedia. Kaufman is the editor-in-chief of the IEEE Transaction on Visualization and Computer Graphics. He has lectured widely and published numerous technical papers in these areas, including the IEEE tutorial book on Volume Visualization. He has been the papers chair and program cochair for Visualization 1990-1994 and the chairman of the IEEE CS Technical Committee on Computer Graphics.

Ph.D. - Ben-Gurion University, Israel, 1977

Phone: (631) 632-8441
Email: Arie.Kaufman@sunysb.edu
URL: http://www.cs.sunysb.edu/~ari/
 

Kathryn L. Kolsky
Scientist

Kathryn Kolsky’s primary research interest is in the development and production of radioisotopes using the BLIP facility, a high-energy charged particle accelerator at Brookhaven National Laboratory. Many of these isotopes have applications in the field of Nuclear Medicine. Of current interest is the development of techniques for the production of no-carrier added tin-117m (an Auger emitter) for tumor therapy. Most malignant tumors express one or more receptor proteins that are absent or subdued in normal cells. Targeting such exclusive proteins with radionuclides to image or treat tumors is a very attractive approach. The targeting moiety most often is an analog of the natural ligand for the receptors. We are developing methods to synthesize Sn-117m labeled precursors that will selectively bind to the estrogen receptor on malignant breast carcinoma, while sparing the surrounding normal tissue.

Ph.D. - Carnegie-Mellon University, 1989

Phone: (631) 344-3578
Email: kolsky@bnl.gov
URL: http://www.bnl.gov/medical/Personel/Kolsky/Kolsky.htm
 

Irvin B. Krukenkamp
Professor

In 1997, Irvin Krukenkamp joined the Stony Brook faculty as professor of surgery and chief of cardiothoracic surgery. Coming from Harvard University, Krukenkamp now directs the Division of Cardiothoracic Surgery, and also co-directs the newly formed Heart Hospital. Performing the only open heart surgery in Suffolk County, he and his team of cardiothoracic surgeons specialize in high-risk and tertiary care types of surgical intervention. Krukenkamp's special clinical interests also include coronary and valve surgery in the octogenarian; and operative management and myocardial protection of the profoundly dysfunctional heart. Krukenkamp's research interests include myocardial mechanics and energetics; myocardial protection by cardioplegia; and new endogenous myoprotective strategies utilizing preconditioning. He is currently the principal investigator or co-investigator of three NIH-funded studies focusing on myocardial protection in the senescent heart; the electrophysiology of potassium channel opening; and the mechanics of ischemic myocardial preconditioning.

M.D. - University of Maryland, 1982

Phone: (631) 444-1820
Email: Irvin.Krukenkamp@sunysb.edu
 

Jerome Z. Liang
Professor of Radiology, Computer Science, and Physics

Jerome Liang focuses his attention on the development of quantitative SPECT systems,
3D virtual endoscopy, and computer aided diagnosis. This work includes creating a quantitative SPECT imaging modality as a cost-effective means for patient diagnosis as well as developing a high resolution PET as a functional research imaging modality. Liang is also striving to create a virtual colonoscopy as a cost-effective procedure for colon screening and to construct an automatic method for brain-tissue segmentation for diagnosis of disorders. In addition, he plans to build various models, in terms of physics, mathematics, and statistics, to simulate the practical problems above and then to validate the models by experiments. Liang has published his findings in journals such as Magnetic Resonance Medicine.

Ph.D. - City University of New York, 1987

Phone: (631) 444-7837
Email: jzl@mil.sunysb.edu
URL: http://www.mil.sunysb.edu/iris/jzl/jzl.html
 

Jean Logan
Scientist

Jean Logan has worked in the positron emission tomography (PET) group at BNL since her post-doctoral in theoretical chemistry. Her research interests are primarily the kinetic modeling of data from PET experiments. PET measures radioactivity concentration in tissue after the introduction of a radiotracer. The PET group has developed radiotracers for a number of brain receptors (for example the dopamine D2 receptor, the dopamine transporter, the norepinephrine transporter) and enzymes (monoamine oxidase A and B which occur in the brain as well as in many peripheral organs). Since PET measures the total radiotracer concentration in the tissue it is necessary to separate the tissue accumulation due to functioning receptor etc. from other processes such as tracer delivery via blood flow. She developed a simple technique for analyzing PET data extracting information related to available receptor concentration that is frequently used in PET research today.

Ph.D. - Louisiana State University, 1976