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Program
Faculty: S
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David
J. Schlyer
Assistant Professor |
 Major
research interests are in the development of new
imaging devices for Positron Emission Tomography
(PET). Current work includes development of a microprobe
for detecting beta particles in a high gamma ray
background area. Applications include measuring
the uptake of positron emitting radiotracers in
very small regions of the brain in rats, measuring
the concentration of radioactivity in blood vessels
and measuring concentrations of radioactivity in
very small volume reaction vessels. Another project
is the development of PET which can be used with
an awake rat. This Amobile PET@ would allow research
in small animals without the influences of anesthesia.
The concept is to use advances in avalanche photodiodes
and monolithic electronics to miniaturize the tomograph.
Additional research interests have been in the production
of radioisotopes for nuclear medicine using charged
particle accelerators. The most recent area of interest
is in the design of targets for low energy, high
beam current linear accelerators.
Ph.D. - University
of California, San Diego, 1976
Phone: (631) 344-4587
Email: schlyer@bnl.gov
URL: http://www.chemistry.bnl.gov/SciandTech/BCIN/PET/schlyer.htm
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Carlos Simmerling
Associate Professor |
|  The goals of a computational chemist are to accurately simulate known properties of molecules, assist in the refinement and interpretation of experimental data and predict the results of future experiments. While quantum mechanical methods can be highly accurate, they are limited in that they currently cannot be applied to large systems such as proteins and nucleic acids, and little or no explicit solvent can be included in the calculations. Since the research in my lab involves relatively large biomolecular systems (such as proteins and nucleic acids) where specific interactions with solvent molecules are often important, we use the methods of molecular mechanics. Typical calculations involve molecular dynamics of the molecule of interest along with thousands of explicit solvent molecules, where the behavior of the molecule as a function of time is used to determine kinetic and thermodynamic properties of the system. These simulations can provide an atomic-detail picture of the behavior of a single molecule, rather than the time- and ensemble-averaged views that come from most experiments.
Ph.D. - University of Illinois at Chicago,1994
Associate Professor
Department of Chemistry
Stony Brook University
Phone: (631) 632-1336
Email: carlos.simmerling@sunysb.edu
URL: http://ws.cc.stonybrook.edu/chemistry/faculty/csimmerling.htm
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Steven
Skiena
Associate Professor |
|  Current
research interests of Steven Skiena focus on computational
biology combinatorial computing environments,
and algorithms for visual computing. Recent projects
include the Stony Brook Algorithm Repositorya
collection of algorithm implementations and other
resources, associated with Skiena's book, The
Algorithm Design Manual; the Ambiguity Resolution
for Overloaded KeyboardsSkiena's patented technology
that uses statistical and grammatical constraints
and algorithmic techniques to resolve the ambiguity
inherent in keyboard overloading with high accuracy;
Combinatoricaa library of 230 Mathematical functions
for combinatorics and graph theory, associated
with Skiena's book Implementing Discrete Mathematics;
Stroll an accurate and efficient fragment assembler
for genome-level DNA sequencing projects; and
Visualizing Objects with Mirrorsray traced graphics
of virtual objects in a carefully constructed
room of mirrors by which Skiena and his research
group literally provide a new way to see the world.
Ph.D. - University
of Illinois, 1988
Phone: (631) 632-9026
Email: Steven.Skiena@sunysb.edu
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Irene
C. Solomon
Associate Professor |
| Research
interests: Reflex and central neural control of
cardiovascular and respiratory function
Ph.D. University of California
Davis, 1994
Email:
icsolomon@notes.cc.sunysb.edu
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Lincoln
D. Stein
Associate Professor |
|  Our
lab is taking a proactive approach to the genome
information explosion by developing databases,
data-analysis tools, and user interfaces to organize,
manage, and visualize that vast body of information.
One current project is the development of a third-party
annotation system for the Caenorhabditis elegans
genome sequence. This system will allow researchers
to add comments and observations to the C. elegans
database and to conveniently view the annotations
of others with a Web browser. The system uses
the ACEDB database in conjunction with the Java
and Perl interfaces that have been developed in
our lab. A second project is the development of
a genome informatics tool kit, a modular collection
of database query tools, sequence-analysis programs,
and user interfaces that will allow biologists
to solve data-management problems without the
assistance of a computer programmer.
M.D. - Harvard Medical
School, 1989
Ph.D. - Harvard University, 1989
Phone: (516) 367-8380
Email: steinl@cshl.org
URL: http://clio1.cshl.org:80/gradschool/stein_.html
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BME SEMINAR SERIES |
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Upcoming Seminar: May 13, 2008
Mechanical Influences on Endothelial Cell Regulation
Natacha DePaola, Ph.D.
more»
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