Mission Statement

Here in the Biomedical Engineering department at Stony Brook University, designing and characterizing heart cell networks and functional heart tissue in the lab is the focus of the Cardiac Cell Engineering Laboratory.

We equally love the engineering and the biomedical component in B-M-E, and strive to combine them to gain a better understanding of how cardiac cells self-organize and function.

We are motivated to provide useful tools for physiomics type of studies, drug and gene therapy testing 3D cellular platforms, an experimental setting for validation of computer models of excitable tissue, and ultimately to contribute to strategies for the regeneration of the heart. This research is multidisciplinary by nature and involves a spectrum of experimental molecular and cell biology procedures, along with the application of design concepts from electrical, optical, mechanical and chemical engineering to create the enabling technology for our studies. Image processing algorithms and computer modeling are essential complementary tools, developed and applied by our team.

Key Research Areas:

• Optical mapping of excitation

• Signal and image processing

• Cardiac cell and tissue engineering

• Mechanisms of arrhythmias