News at BME
Stony Brook Ranked #7 for percent of students from the bottom fifth of the income distribution who end up in the top three-fifths
Stony Brook was recently ranked by the New York Times as one of America's Great Working-Class colleges.
Federal Work Study Position Available Effective Spring 2017
If you have Federal Work Study for the Spring 2017 semester and are looking for a position still. Please send your resume to email@example.com. The position includes filling, clerical tasks, deliveries across campus, etc.
Shu Jia, BME Assistant Professor, Awarded 2 Prestigious Awards
The National Science Foundation and the Defense Advanced Research Projects Agency has funded two projects focused on the development of new super-resolution light microscope for both imaging of cells, tissues and organ systems and specifically will try to develop an understanding of the brain. Congratulations to Shu and his research team!
Postdoctoral Position Available
We are seeking a motivated postdoctoral fellow to join our multi-institution team in the research of novel applications of optical spectroscopy in medicine and the device-on-chip development. Qualified candidate should have a Ph.D. degree in biomedical engineering, electrical engineering or related fields with strong interest in medical device, proven experience in optical spectroscopy and field programmable gate array (FPGA) technology in high performance computing, and electronic and optical system integration.
Amna Haider, BME Junior, Featured on PSEG LI Investing in the Future of Stem
Congratulations to Amna for her research work this summer, funded by PSEG LI, to look into the role of cocaine on bone mechanical/physical properties. Amna is currently working on the direction of Drs Ete Chan and Clint Rubin. Bruce Coluccio, a BME Sophomore, and Robert Bruce, a Physics Major, also work with Drs Chan and Rubin over the summer in this project. Congratulations to all for their important work.
Assistant Professor, Shu Jia, has been named as a DARPA Young Faculty Awardee
The awarded project entitled: "Wavefront-Engineered, High-Speed Super-Resolution Microscopy for Nanometer-Scale, Live-Tissue Imaging" is at the forefront of super resolution microscopy.
The advancement of our understanding of biology has been greatly reliant on observations of cells. Light microscopy, especially fluorescence microscopy, has evolved to observe smaller specimens with greater resolution. The spatial resolution of a microscope is defined as the smallest distance in an image in which two distinct points can be distinguished. Because of the diffraction of light, resolution had previously been thought to have a theoretical limit from what is called Abbe's diffraction limit of light (~200-300 nanometers). Recent emergence of super-resolution imaging techniques has surpassed this limit, allowing visualization of cellular and sub-cellular structures with ~10-20 nanomater resolution at the near-molecular-scale. This advance provides thriving opportunities for exploring the complex structure, dynamics and function of biological molecules. Due to the significant impact of these new techniques, the 2014 Nobel Prize in Chemistry was awarded to the development of super-resolution fluorescence microscopy.
The research in the Jia Laboratory aims to enhance this resolving power across unexplored regimes in space and time to attain a better understanding of the molecular basis for the functions of tissues and organisms. To achieve the goal, the group investigates the physical and engineering principles underlying single-molecule imaging in complex biological materials, and utilizes these principles to develop new biophotonic methods for super-resolution microscopy. These methods include optical physics, optical wavefront engineering, single-molecule biophysics, adaptive optics, phase microscopy, large-data processing, advanced instrumentation, nano-fabrication, etc.
One super-resolution imaging method currently under investigation is called stochastic optical reconstruction microscopy (STORM), which relies on imaging of single molecules to reconstruct fluorescence images with sub-diffraction-limit resolution. In biological systems, how these single-molecule mechanisms are integrated over larger scales is critical for understanding physiological functions and disease initiation of complex biological systems. There remains a great demand in an enabling technology to extract such single-molecule information and dynamics across large volumes of specimen with ultra-high spatiotemporal resolution.
The DARPA award will support the lab's development of a new super-resolution microscopy system for in vivo investigations of cell, tissue and organ functions. The research will base on the lab's expertise in a technique called point spread function engineering, which can modify how light is propagated within an imaging system to achieve better imaging capability. By exploring and implementing a new type of optical non-diffracting waveforms, the light within a microscope can propagate in a dramatically different way from normal light. One typical feature is that it will not spread out as much as described by the usual diffraction effect of light. This allows people to image further deeper into biological samples. In addition, it also provides better 3D resolution and is more robust to scattering effect in biological tissues.
First trained as an applied physicist and electrical engineer and later into a bioimaging expert, Dr. Jia is passionate about advancing imaging technology with new physical concepts and engineering design. The highly interdisciplinary team consists of experts from physics, computer science, engineering, and biology. In collaboration with researchers both within the Department of Biomedical Engineering and elsewhere, the lab expects their new technologies would provide new insights and solutions to challenges in biological and ultimately clinical research.
James Scheuermann wins First Place
Congratulations to BME Ph.D. Candidate, James Scheuermann who won first place in the John R. Cameron Young Investigators Competition held by the American Association of Physicists in Medicine.
Ete Chan wins SUNY Funding to Develop a Virtual Lab
Ete Chan, Assistant Professor, has received funding which will explore and develop the creation of virtual labs for Biomedical Engineering students. She is the leader of a group of biomedical engineering faculty and students and computer science faculty and students that will implement this project. Congratulations.
ASEE TV Highlights CEAS Research and Educational Mission
Dr. Ete Chan and BME Junior Amna Haider were featured on the ASEE Highlights of CEAS Research and Education. Congratulations.